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Anti-PEX6 Antibody

CAT: 1303-75-285Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-285Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Peroxisomal Biogenesis Factor 6 is encoded by the gene PEX6. PEX6 is a member of the AAA ATPase family. PEX6 is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 receptor activity. PEX6 is expressed in the retina. Diseases associated with PEX6 include Peroxisome Biogenesis Disorder 4A and Heimler Syndrome 2.
Description
Our Anti-PEX6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N233/8. It detects human and rat PEX6, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Short Description
Our Anti-PEX6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N233/8. It detects human and rat PEX6, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.
Synonyms
Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1)
Gene Name
PEX6 PXAAA1
UniProt
Q13608
Host
Mouse
Reactivity
Human and Rat
Immunogen
Fusion protein amino acids 2-294 (N-terminus) of human PEX6 (accession number Q8BR86-3) produced recombinantly in E. Coli
Target
PEX6
Clonality
Monoclonal
Isotype
IgG1
Clone
N233/8
Type
Primary Antibody
Applications
WB, ICC, ELISA
Field of Research
Rare Diseases
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
100 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity reported
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_2315903

UniProtKB · Q13608

Peroxisomal ATPase PEX6

PEX6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13608
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PEX6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
Q5T8W1, Q8WYQ0, Q8WYQ1, Q8WYQ2, Q99476
Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Amelogenesis imperfectaDeafnessDisease variantPeroxisome biogenesis disorderZellweger syndrome

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell projectionCytoplasmMembranePeroxisome

Molecular function

Hydrolase

PTM

Methylation

Biological process

Peroxisome biogenesis

Technical term

Proteomics identificationReference proteome

Domain

Repeat

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