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Anti-SynCAM4 Antibody

CAT: 1303-75-247Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-247Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SynCAM4 cell adhesion molecule, Immunoglobulin Superfamily, Member 4C (IGSF4C), or Nectin-Like Protein 4 (NECL4) is encoded by the gene CADM4 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam4 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in several tissue types including brain, kidney and liver. Diseases associated with with this gene include Small Intestine Adenocarcinoma.
Description
Our Anti-SynCAM4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N244/5. It is KO validated, detects human, mouse, and rat SynCAM4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Short Description
Our Anti-SynCAM4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N244/5. It is KO validated, detects human, mouse, and rat SynCAM4, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.
Synonyms
Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)
Gene Name
Cadm4 Igsf4c Necl4 Tsll2
UniProt
Q8R464
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 1-321 (signal peptide and extracellular N-terminus) of mouse SynCAM4 (accession number Q8R464) produced recombinantly in E. Coli
Target
SynCAM4
Clonality
Monoclonal
Isotype
IgG1
Clone
N244/5
Type
Primary Antibody
Applications
WB, IHC, ICC, ELISA
Field of Research
Cell Adhesion Molecules
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
43 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
IHC Dilution
1:100
WB Dilution
1:1000
Specificity
Does not cross-react with other SynCAMs (based on KO validation results)
ICC Dilution
1:500
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Mouse
WB Brain Quality Control
1
Conjugate
Unconjugated
RRID
AB_10676101

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