Products for Research Use Only

Anti-SynCAM1 Antibody

CAT: 1303-75-120Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-120Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.
Description
Our Anti-SynCAM1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Short Description
Our Anti-SynCAM1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.
Synonyms
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene Name
Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1
UniProt
Q8R5M8
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli
Target
SynCAM1
Clonality
Monoclonal
Isotype
IgG1
Clone
L45/30
Type
Primary Antibody
Applications
WB, ICC, ELISA
Field of Research
Cell Adhesion Molecules
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.47
Molecular Weight
50 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity with SynCAM2 or SynCAM3
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Mouse
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_2068036