Products for Research Use Only
RegisterLogin

Didox

CAT: 0804-HY-19387-06Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19387-06Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.
CAS Number
69839-83-4
Product Name Alternative
NSC-324360
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Didox.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NO)C1=CC=C(O)C(O)=C1
Molecular Formula
C7H7NO4
Molecular Weight
169.13
Precautions
H302, H312, H332
References & Citations
[1]Matsebatlela TM, et al. 3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages. Chem Biol Interact. 2015 May 25;233:95-105.|[2]Cook GJ, et al. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. PLoS One. 2014 Nov 17;9 (11) :e112619.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Chemical Information

N,3,4-Trihydroxybenzamide

N-3,4-tridhydroxybenzamide is a member of benzoic acids.

CAS Number69839-83-4
PubChem CID3045
IUPAC NameN,3,4-trihydroxybenzamide
Molecular FormulaC7H7NO4
Molecular Weight169.13
XLogP0.4
Topological Polar Surface Area89.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count12
Formal Charge0
Complexity173
SMILES
C1=CC(=C(C=C1C(=O)NO)O)O
InChI
InChI=1S/C7H7NO4/c9-5-2-1-4(3-6(5)10)7(11)8-12/h1-3,9-10,12H,(H,8,11)
InChIKey
QJMCKEPOKRERLN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N,3,4-Trihydroxybenzamide
CAS: 69839-83-4
CID: 3045
Formula: C7H7NO4
MW: 169.13
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight169.13
XLogP30.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass169.03750770
Monoisotopic Mass169.03750770
Topological Polar Surface Area89.8 Ų
Heavy Atom Count12
Formal Charge0
Complexity173
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-RS03767DIDO1 Human Pre-designed siRNA Set A

Alternative Products

CatalogName
C02281-01Didox
A16304-5Didox 5mg
A16304-100Didox 100mg
A16304-500Didox 500mg
A16304-50Didox 50mg
A16304-25Didox 25mg
A16304-10Didox 10mg
A16304-10mM-DDidox 10mM * 1mL in DMSO

Popular Products