PI3K-IN-52

• UNSPSC Description:

  PI3K-IN-52 (compound cis 6g) is a potent inhibitor of PI3K, with IC50 of 0.23 μM in HGC-27 cells. PI3K-IN-52 plays an important role in cancer research[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3k-in-52.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C2C(C(OC3CCOCC3)=CC(C4=CC(/N=N\C5=CC=CC=C5F)=C(N=C4)OC)=C2)=NC=N1

• Molecular Weight:

  473.50

• References & Citations:

  [1]Yan Zhang, et al. Design, Synthesis, and Bioevaluation of Novel Reversibly Photoswitchable PI3K Inhibitors Based on Phenylazopyridine Derivatives toward Light-Controlled Cancer Treatment. J Med Chem. 2024 Feb 20.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported