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PI3K-IN-52

CAT: 0804-HY-161301Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161301Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3K-IN-52 (compound cis 6g) is a potent inhibitor of PI3K, with IC50 of 0.23 μM in HGC-27 cells. PI3K-IN-52 plays an important role in cancer research[1].
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-in-52.html
Solubility
10 mM in DMSO
Smiles
CC1=C2C(C(OC3CCOCC3)=CC(C4=CC(/N=N\C5=CC=CC=C5F)=C(N=C4)OC)=C2)=NC=N1
Molecular Formula
C26H24FN5O3
Molecular Weight
473.50
References & Citations
[1]Yan Zhang, et al. Design, Synthesis, and Bioevaluation of Novel Reversibly Photoswitchable PI3K Inhibitors Based on Phenylazopyridine Derivatives toward Light-Controlled Cancer Treatment. J Med Chem. 2024 Feb 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported