Elexacaftor-d3
CAT:
804-HY-111772S1-01
Size:
500 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Elexacaftor-d3
- UNSPSC Description: Elexacaftor-d3 (VX-445-d3) is the deuterium labeled Elexacaftor (HY-111772)[1].
- Target Antigen: Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Others
- Field of Research: Inflammation/Immunology
- Purity: 99.23
- Solubility: 10 mM in DMSO
- Smiles: CC1(C)C[C@H](C)CN1C2=C(C(NS(C3=CN(C([2H])([2H])[2H])N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2
- Molecular Weight: 600.67
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Keating D, et al. VX-445-Tezacaftor-VX-770 in Patients with Cystic Fibrosis and One or Two Phe508del Alleles. N Engl J Med. 2018 Oct 25;379(17):1612-1620.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported