3-HTC

• Description:

  3-HTC is a chemical fluorescent probe. 3-HTC reacts reversibly with thiols and disulfides, and can be used to measure dynamic GSH/GSSH ratios in vitro as well as to monitor the reversible redox status of whole cell lysates (λmax: 448 nm in its reduced thiolate form, and a λmax 370-410 nm for the oxidized mixed disulfide) [1].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/3-htc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C(C2=NC3=CC=CC=C3S2)=CC4=CC=C(S)C=C4O1

• Molecular Formula:

  C16H9NO2S2

• Molecular Weight:

  311.38

• References & Citations:

  [1]Reddie KG, et al. Fluorescent coumarin thiols measure biological redox couples. Org Lett. 2012 Feb 3;14 (3) :680-3.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [1356543-39-9]