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Chlorahololide C

CAT: 0804-HY-N8404-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8404-01Size:1 mg
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Description
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM[1].
CAS Number
1007859-25-7
UNSPSC
12352005
Target
Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/chlorahololide-c.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COC(/C(C)=C1C2=C([C@]([C@@]3([H])[C@]4([H])C3)([C@H](C/1=O)O)C)[C@]4(O)C[C@]([C@@]5([C@@](C([C@]6([H])[C@@]5([H])C6)=C)([H])[C@H]7OC(C)=O)C)([H])[C@@]28C7=C(C(O8)=O)C)=O
Molecular Formula
C33H36O9
Molecular Weight
576.63
References & Citations
[1]Yang SP, et, al. Chlorahololides C-F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius. Tetrahedron. 2008 Feb; 64 (9) :2027-2034.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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