PARP-2-IN-1
CAT:
804-HY-102035-04
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PARP-2-IN-1
- CAS Number: 2115698-83-2
- UNSPSC Description: PARP-2-IN-1 is a potent and selective PARP-2 inhibitor with an IC50 of 11.5 nM.
- Target Antigen: PARP
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/PARP-2-IN-1.html
- Purity: 99.56
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NC1=CC(CN2C(NC(C3=C2C=CC=C3)=O)=O)=CN=C1F)[C@H]4CCN(CC(F)(F)F)C4
- Molecular Weight: 465.40
- References & Citations: [1]Zhao H, et al. Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors. Bioorg Med Chem. 2017 Aug 1;25(15):4045-4054.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported