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HPGDS inhibitor 2

CAT: 0804-HY-126134-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126134-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1].
CAS Number
2101626-26-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hpgds-inhibitor-2.html
Purity
99.72
Solubility
DMSO : ≥ 150 mg/mL
Smiles
FC(F)OC1=CC=C2C(N=CC(C(N[C@@H]3CC[C@@H](C(C)(C)O)CC3)=O)=C2)=C1
Molecular Formula
C20H24F2N2O3
Molecular Weight
378.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27 (8) :1456-1478.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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