BC11-38

CAT: 0804-HY-108618-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-108618-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].
CAS Number
[686770-80-9]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/bc11-38.html
Purity
99.42
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C2=C(CCS2)N=C(SCCC)N1C3=CC=CC=C3
Molecular Formula
C15H16N2OS2
Molecular Weight
304.43
References & Citations
[1]Ceyhan O, et al. Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol. 2012;19 (1) :155-163.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10; PDE11

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