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EN1033

CAT: 0013-GTR19280536-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19280536-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EN1033 is a covalent immunomodulatory transcription factor 5/8 (IRF5/8) degrader. It disrupts and degrades IRF5 and IRF8 by covalently targeting cysteine residues C28 and C223, thereby inhibiting their pro-inflammatory transcriptional activity, such as reducing mRNA levels of IL1A, IL1B, and CCL2. EN1033 is applicable in research of autoimmune and inflammatory diseases.
CAS Number
2193367-28-9
Smiles
O=C (C=C) N1C=2C=CC=CC2CN3CCCC3C1
Molecular Formula
C15H18N2O
Molecular Weight
242.32
Notes
For research use only.

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