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Arg-PEG1-Dasa

CAT: 0013-GTR19277063-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277063-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arg-PEG1-Dasa is a mini-PROTAC that targets BCR-ABL. It is capable of inducing BCR-ABL degradation (EC50 = 0.85 nM) and demonstrates antiproliferative activity in K562 cells (IC50 = 0.36 nM) . Arg-PEG1-Dasa is applicable for research in chronic myeloid leukemia.
CAS Number
3037776-67-0
Smiles
N (C1=CC (=NC (C) =N1) N2CCN (CCOC (CCOCCNC ([C@H] (CCCNC (=N) N) N) =O) =O) CC2) C=3SC (C (NC4=C (C) C=CC=C4Cl) =O) =CN3
Molecular Formula
C33H47ClN12O5S
Molecular Weight
759.33
Storage Conditions
-20°C
Notes
For research use only.

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