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Lys-PEG3-BA

CAT: 0013-GTR19277048-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277048-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lys-PEG3-BA is a PROTAC degrader targeting EML4-ALK/EGFR, with DC50 values of 1.32 μM for H3122 cells (expressing EML4-ALK fusion protein) and 19.66 μM for H1975 cells (with EGFRL858R/T790M mutations) . In vitro studies show that Lys-PEG3-BA can inhibit the proliferation of non-small cell lung cancer cells by modulating the ubiquitin-proteasome system. Lys-PEG3-BA is applicable for research related to non-small cell lung cancer.
CAS Number
3057939-67-7
Smiles
O (C) C=1C=C (C=CC1NC=2N=C (NC3=C (P (C) (C) =O) C=CC=C3) C (Cl) =CN2) N4CCN (C (CCOCCOCCOCCNC ([C@H] (CCCCN) N) =O) =O) CC4
Molecular Formula
C38H57ClN9O7P
Molecular Weight
818.35
Storage Conditions
-20°C
Notes
For research use only.

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