Products for Research Use Only
RegisterLogin

Gly-PEG3-BA

CAT: 0013-GTR19277036-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19277036-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gly-PEG3-BA is a PROTAC degrader that targets EML4-ALK. It effectively degrades the EML4-ALK protein in H3122 cells (EML4-ALK positive) with a DC50 of 0.50 μM. In H1975 cells (EGFRL858R/T790M double mutant), Gly-PEG3-BA significantly reduces the levels of the EGFR mutant (L858R/T790M) protein, with a DC50 of 20.15 μM. Additionally, Gly-PEG3-BA exhibits strong antiproliferative activity against H3122 cells and H1975 cells, with IC50 values of 0.84 μM and 20.74 μM, respectively. It is useful for research related to non-small cell lung cancer.
CAS Number
3057939-66-6
Smiles
O=C (NCCOCCOCCOCCC (=O) N1CCN (C2=CC=C (NC3=NC=C (Cl) C (=N3) NC=4C=CC=CC4P (=O) (C) C) C (OC) =C2) CC1) CN
Molecular Formula
C34H48ClN8O7P
Molecular Weight
747.23
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19277082-01Pro-PEG3-BA
GTR19277048-01Lys-PEG3-BA
GTR19226213-01Gly-Gly-Gly-PEG3-TCO
GTR19280535-01Gly-Gly-Gly-PEG3-TCO TFA
GTR19277086-01DBCO-PEG3-Gly
GTR19226510-01Gly-PEG3-amine
GTR19226179-01Gly-PEG3-endo-BCN
GTR19227457-01Boc-gly-PEG3-endo-BCN
GTR19227468-01Boc-Gly-amido-C-PEG3-C3-amine
GTR19244765-01Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA

Alternative Products

CatalogName
MBS5770851Gly-Gly-Gly-PEG3-TCO
BIPG2294-01Gly-Gly-Gly-PEG3-methyltetrazine
HY-141190AGly-Gly-Gly-PEG3-TCO (TFA)
T15392-01Gly-PEG3-amine
C56985-25MGNH2-Gly-Gly-PEG3-Azide
HY-140080Gly-PEG3-endo-BCN
BIPG2415-01Boc-Gly-PEG3-endo-BCN
571884Gly-PEG3-amine, TFA salt
BIPG2650-01Bis- (Boc-Gly-amido-propane) -PEG3
HY-140237Boc-Gly-amido-C-PEG3-C3-amine

Popular Products