Products for Research Use Only
RegisterLogin

PROTAC SMARCA2/4 degrader-39

CAT: 0013-GTR19275156-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19275156-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PROTACSMARCA2/4 degrader-39 (Compound 7) is a selective PROTAC degrader targeting SMARCA2 (BRM) and SMARCA4 (BRG1) . This compound holds potential for research in oncology, including studies on non-small cell lung cancer and colorectal cancer.
CAS Number
3099581-74-2
Smiles
C (C) [C@@]12N (C=3C (NC1) =NN=C (C3) C4=C (O) C=CC=C4) C[C@H] (OC5=C (C) C=C (C (=O) N6CCN (CC6) C=7C=C8C (=CC7) CN (C8=O) [C@@H]9C (=O) NC (=O) CC9) C=N5) C2
Molecular Formula
C41H43N9O6
Molecular Weight
757.85
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(3S)-3-[5-[4-[6-[[(4R,6S)-6-ethyl-12-(2-hydroxyphenyl)-2,8,10,11-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-trien-4-yl]oxy]-5-methylpyridine-3-carbonyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
CAS Number3099581-74-2
PubChem CID176880220
IUPAC Name(3S)-3-[5-[4-[6-[[(4R,6S)-6-ethyl-12-(2-hydroxyphenyl)-2,8,10,11-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-trien-4-yl]oxy]-5-methylpyridine-3-carbonyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
Molecular FormulaC41H43N9O6
Molecular Weight757.8
XLogP2.9
Topological Polar Surface Area173
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Heavy Atom Count56
Formal Charge0
Complexity1500
SMILES
CC[C@@]12C[C@H](CN1C3=CC(=NN=C3NC2)C4=CC=CC=C4O)OC5=NC=C(C=C5C)C(=O)N6CCN(CC6)C7=CC8=C(CN(C8=O)[C@H]9CCC(=O)NC9=O)C=C7
InChI
InChI=1S/C41H43N9O6/c1-3-41-19-28(22-50(41)33-18-31(45-46-36(33)43-23-41)29-6-4-5-7-34(29)51)56-38-24(2)16-26(20-42-38)39(54)48-14-12-47(13-15-48)27-9-8-25-21-49(40(55)30(25)17-27)32-10-11-35(52)44-37(32)53/h4-9,16-18,20,28,32,51H,3,10-15,19,21-23H2,1-2H3,(H,43,46)(H,44,52,53)/t28-,32+,41+/m1/s1
InChIKey
YAMMHJFFVIPAAV-WFSJYAARSA-N
Chemical Structure
2D Structure
2D structure of (3S)-3-[5-[4-[6-[[(4R,6S)-6-ethyl-12-(2-hydroxyphenyl)-2,8,10,11-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-trien-4-yl]oxy]-5-methylpyridine-3-carbonyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
CAS: 3099581-74-2
CID: 176880220
Formula: C41H43N9O6
MW: 757.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight757.8
XLogP32.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Exact Mass757.33363013
Monoisotopic Mass757.33363013
Topological Polar Surface Area173 Ų
Heavy Atom Count56
Formal Charge0
Complexity1500
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19237905-01PROTAC SMARCA2 degrader-4
GTR19238454-01PROTAC SMARCA2/4-degrader-4
GTR19250386-01PROTAC SMARCA2/4 degrader-36
GTR19239935-01PROTAC SMARCA2/4-degrader-35
GTR19239259-01PROTAC SMARCA2/4-degrader-25
GTR19239176-01PROTAC SMARCA2/4-degrader-28
GTR19238897-01PROTAC SMARCA2/4-degrader-32
GTR19238665-01PROTAC SMARCA2/4-degrader-1
GTR19238140-01PROTAC SMARCA2/4-degrader-11
GTR19237624-01PROTAC SMARCA2/4-degrader-27

Alternative Products

CatalogName
HY-178225PROTAC SMARCA2/4 degrader-39
T89436-01PROTAC SMARCA2 degrader-4
HY-159455PROTAC SMARCA2/4-degrader-4
HY-159461PROTAC SMARCA2/4-degrader-9
HY-162744PROTAC SMARCA2/4-degrader-31
T200532-01PROTAC SMARCA2/4-degrader-2
T89900-01PROTAC SMARCA2/4-degrader-27
T89602-01PROTAC SMARCA2/4-degrader-10
T88983-01PROTAC SMARCA2/4-degrader-5
T88872-01PROTAC SMARCA2/4-degrader-8

Popular Products