Products for Research Use Only
RegisterLogin

Cot-IN-5

CAT: 0013-GTR19275016-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19275016-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cot-IN-5 (compound 1) is a potent ATP-competitive inhibitor of cancer Osaka thyroid (COT) . It effectively blocks the autophosphorylation of the COT kinase.
CAS Number
1798303-75-9
Smiles
C (=C/C (O) =O) \C1=CC (C2=CC3=C (C=C2) C=CC=C3) =CN=C1N
Molecular Formula
C18H14N2O2
Molecular Weight
290.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(E)-3-(2-amino-5-naphthalen-2-yl-3-pyridinyl)prop-2-enoic acid
CAS Number1798303-75-9
PubChem CID171921859
IUPAC Name(E)-3-(2-amino-5-naphthalen-2-yl-3-pyridinyl)prop-2-enoic acid
Molecular FormulaC18H14N2O2
Molecular Weight290.3
XLogP3.3
Topological Polar Surface Area76.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count22
Formal Charge0
Complexity423
SMILES
C1=CC=C2C=C(C=CC2=C1)C3=CC(=C(N=C3)N)/C=C/C(=O)O
InChI
InChI=1S/C18H14N2O2/c19-18-15(7-8-17(21)22)10-16(11-20-18)14-6-5-12-3-1-2-4-13(12)9-14/h1-11H,(H2,19,20)(H,21,22)/b8-7+
InChIKey
VZCJIXLWKDIMAV-BQYQJAHWSA-N
Chemical Structure
2D Structure
2D structure of (E)-3-(2-amino-5-naphthalen-2-yl-3-pyridinyl)prop-2-enoic acid
CAS: 1798303-75-9
CID: 171921859
Formula: C18H14N2O2
MW: 290.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight290.3
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass290.105527694
Monoisotopic Mass290.105527694
Topological Polar Surface Area76.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity423
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19164426COT-BSA
GTR19273917-01Cot-IN-4
GTR18076397COT antibody
GTR19150567COT-BSA conj.
GTR19238851-01Cot inhibitor-3
GTR19206173-01Cot inhibitor-1
GTR19206171-01Cot inhibitor-2
GTR18699427-01COT Mouse mAb
GTR18198618Cot Polyclonal Antibody
GTR18198617COT Polyclonal Antibody

Alternative Products

CatalogName
399408-01COT
70R-30667COT antibody
HY-163556COT/BSA
535003-01COT discontinued
ABT-DOA-B175COT Cassette
HY-178726Cot-IN-4
ABT-DOA-A141COT Strip
bs-3632PBCOT-BSA
abx033760-01Proto-Oncogene C-Cot (COT) Antibody
MBS515539-01COT, Active

Popular Products