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FQI2-34

CAT: 0013-GTR19274899-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274899-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FQI2-34 is an orally active small-molecule allosteric inhibitor of TFCP2 (LSF) . It binds directly to the LSF protein (Ki = 63 nM), inhibits LSF oligomerization, and effectively suppresses LSF transcriptional activity (IC50 = 48 nM), thereby disrupting the SF-DNA interaction. FQI2-34 exhibits significant antiproliferative effects on Huh7 cells and induces tumor regression in mouse models. This compound can be utilized for hepatocellular carcinoma research.
CAS Number
2762499-38-5
Smiles
O=C1C=C (C=2C=CC (=CC2OCC) N (C) C) C=3C=C4OCOC4=CC3N1
Molecular Formula
C20H20N2O4
Molecular Weight
352.39
Storage Conditions
-20°C
Notes
For research use only.

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