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BMS-135

CAT: 0013-GTR19274881-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274881-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-135 is a potent and selective ATP-competitive inhibitor of casein kinase 2 (CK2), with IC50 values of 0.8 nM for CK2α and 0.3 nM for CK2α' isoforms. It mimics the structure of ATP, binding to the active site of CK2 and inhibiting its serine/threonine phosphorylating activity. BMS-135 effectively inhibits cell proliferation and demonstrates antitumor properties, making it useful for research in colon cancer.
CAS Number
1541248-36-5
Smiles
N (CC) C=1C=2N (C (C#N) =CN2) N=C (NC3=C (Cl) C (=CC (C#N) =C3) N4C[C@@H] (O) [C@H] (NC (OC) =O) CC4) N1
Molecular Formula
C22H23ClN10O3
Molecular Weight
510.94
Storage Conditions
-20°C
Notes
For research use only.

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