WY-135

• Target:

  ROS|||ALK|||ROS Kinase

• Related Pathways:

  Immunology/Inflammation|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively) .

• Smiles:

  N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4C=C(CN5CCN(C)CC5)N=N4)=NC=C2Cl

• Molecular Formula:

  C28H34ClN9O3S

• Molecular Weight:

  612.15

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2163060-83-9