COX-1-IN-5

CAT: 0013-GTR19274811-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274811-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

COX-1-IN-5 (example 13, compound PS13) is a potent and selective COX-1 inhibitor with an IC50 of 1 nM, significantly more selective for COX-1 over COX-2 (COX-2 IC50 > 0.1 μM) by over 1000-fold. It demonstrates substantial anti-inflammatory, antipyretic, analgesic, antithrombotic, and anticancer activities. COX-1-IN-5 is applicable in the study of COX-mediated diseases such as inflammation and pain. When radiolabeled with 11C, it serves as a selective PET tracer for systemic imaging of COX-1 distribution and target binding in vivo.

CAS Number

524699-85-2

Smiles

FC (F) (F) COC=1N=C (C=2C=CC (OC) =CC2) N (N1) C3=CC=C (OC) C=C3

Molecular Formula

C18H16F3N3O3

Molecular Weight

379.34

Storage Conditions

-20°C

Notes

For research use only.

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GTR19250023-01	Cox B-IN-1
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Alternative Products

Catalog	Name
HY-146675	COX/5-LOX-IN-1
T13263-01	COX/5-LO-IN-1
T79594-01	COX-1/2-IN-5
HY-146294	COX-2/5-LOX-IN-1
C7904-89C	COX 4-1 (COX IV-1)
BA5939-1	COX-2-IN-5
MO15113	COX-1
HY-162167	COX-1-IN-1
YP-W80264-01	Porcine COX-1 (COX-1) ELISA Kit
HY-179509	COX-2/5-LOX-IN-5

COX-1-IN-5

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