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RXR antagonist 6

CAT: 0013-GTR19274610-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274610-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RXR antagonist 6 (Compound 34) is a selective partial antagonist of the retinoid X receptor (RXR) . It exhibits no agonistic activity on human RXRα/β/γ subtypes, but it effectively inhibits receptor activation induced by full RXR agonists such as Bezafibrate, with an IC50 value of 2.7 μM. Additionally, RXR antagonist 6 can enhance PMA-induced differentiation of THP-1 cells and is applicable in research related to cancer, metabolic disorders, and neurological diseases, including lymphoma.
Storage Conditions
-20°C
Notes
For research use only.

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