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(±) 8 (9) -EET

CAT: 0013-GTR19275157-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275157-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) 8 (9) -EET is a principal metabolite of Arachidonic Acid formed via the cytochrome P450 epoxygenase pathway. It serves as an effective substrate for COX-1 and COX-2. In HEK293 cells, (±) 8 (9) -EET activates PPARα and suppresses IL-1β-induced NF-κB activity through both PPARα-dependent and independent mechanisms. The (8S,9R) -isomer ((8S,9R) -EET) induces vasoconstriction, reducing renal plasma flow and glomerular filtration rate.
CAS Number
184488-44-6
Smiles
C (/C=C\C/C=C\CCCCC) C1C (C/C=C\CCCC (O) =O) O1
Molecular Formula
C20H32O3
Molecular Weight
320.47
Storage Conditions
-20°C
Notes
For research use only.

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