Products for Research Use Only

F3288-0031

CAT: 0013-GTR19274298-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274298-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
F3288-0031 is an allosteric inhibitor of the norepinephrine transporter (NET), demonstrating a 73.5% inhibition rate at a concentration of 20 μM. It binds to NET, stabilizing its inward-open state, and shows preferential inhibitory activity against NET/SERT, with a pIC50 of 5.9. No off-target functional activity has been detected for F3288-0031. Furthermore, it exhibits significant antidepressant-like efficacy without interfering with motor functions. This compound is applicable in the study of depression and related neuropsychiatric disorders.
CAS Number
926493-93-8
Smiles
OC (COC1=CC=C (C=CC) C=C1OC) CN2CCN (CC=3C=CC=CC3) CC2
Molecular Formula
C24H32N2O3
Molecular Weight
396.53
Storage Conditions
-20°C
Notes
For research use only.