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VHL Ligand 38

CAT: 0013-GTR19274011-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274011-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VHL Ligand 38 (Compound 1) is a competitive inhibitor of the E3 ubiquitin ligase VHL, demonstrating IC50 values of 4.1 μM and 7.0 μM in 1% and 10% DMSO solutions, respectively. It features a hydroxyproline residue and an isoxazole acetamide moiety, and effectively inhibits the binding of the fluorescence peptide derived from HIF1α (FAM-DEALA-Hyp-YIPD) to VHL.
CAS Number
1360616-29-0
Smiles
C (CC=1ON=C (C) C1) (=O) N2[C@H] (C (NCC3=CC=C (C=C3) C4=CN=CO4) =O) C[C@@H] (O) C2
Molecular Formula
C21H22N4O5
Molecular Weight
410.43
Storage Conditions
-20°C
Notes
For research use only.

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