Products for Research Use Only
RegisterLogin

GPX4-IN-21

CAT: 0013-GTR19273799-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19273799-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GPX4-IN-21 (Compound 4d) is a selective inhibitor of glutathione peroxidase 4 (GPX4) . It induces ferroptosis and decreases the levels of ferroptosis-related proteins SLC7A11, SLC11A2, and GPX4. GPX4-IN-21 also promotes the accumulation of reactive oxygen species (ROS) and malondialdehyde (MDA) . This compound exhibits potent antiproliferative activity against melanoma, with an IC50 value of 9.42 μM in A375 cells. GPX4-IN-21 is applicable in cancer research, particularly for studies on melanoma.
CAS Number
3014384-72-3
Smiles
O=C (NC1=CC=C2OCC (=O) NC2=C1) C3=CC=CC (=C3) C=4N=NN (C4) C=5C=CC=C (Cl) C5
Molecular Formula
C23H16ClN5O3
Molecular Weight
445.86
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19239292-01GPX4-IN-14
GTR19238382-01GPX4-IN-11
GTR19219705-01GPX4-IN-6
GTR18781922-01GPX4 Antibody
GTR18242745-01GPX4 Antibody
GTR18124968GPX4 Antibody
GTR18194115-01GPX4 Antibody
GTR18186712Gpx4 Antibody
GTR19219872-01GPX4 24
GTR17946066-01GPX4 Antibody

Alternative Products

CatalogName
P45367GPX4
BA3428-100GPX4-IN-6
BA3420-10GPX4-IN-5
BA3452-1GPX4-IN-2
70R-17589GPX4 antibody
HY-163995-01GPX4-IN-13
HY-149923-01GPX4-IN-4
HY-162716GPX4-IN-10
T88965-01GPX4-IN-11
509990GPX4 discontinued

Popular Products