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Ferroptosis-IN-21

CAT: 0013-GTR19273666-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273666-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ferroptosis-IN-21 is an inhibitor of ferroptosis that combats renal ischemia-reperfusion injury by directly scavenging peroxy free radicals to prevent cell death. It demonstrates broad-spectrum, nanomolar-level inhibitory potency against various ferroptosis inducers in renal tubular epithelial cells and effectively suppresses the accumulation of lipid reactive oxygen species (ROS) . Additionally, Ferroptosis-IN-21 significantly alleviates renal ischemia-reperfusion injury in mice, as evidenced by improved histological damage and functional impairment, reduced expression of inflammatory cytokines, and decreased levels of lipid peroxidation biomarkers such as 4-hydroxynonenal. Ferroptosis-IN-21 is a potential candidate in research for developing ferroptosis-targeted therapeutics.
CAS Number
6640-50-2
Smiles
OC1=CC=CC2=C1NCCC2
Molecular Formula
C9H11NO
Molecular Weight
149.19
Storage Conditions
-20°C
Notes
For research use only.

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