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Ferroptosis-IN-20

CAT: 0013-GTR19263194-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263194-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ferroptosis-IN-20 (Compound 34a) is an inhibitor of ferroptosis targeting voltage-dependent anion channels (VDAC) with an EC50 of 24.2 nM. It prevents VDAC oligomerization and lipid peroxidation. Additionally, Ferroptosis-IN-20 reduces ROS levels, diminishes TFR1-mediated iron uptake, inhibits Fe2+ levels, and restores glutathione (GSH) levels. It also alleviates acute kidney injury (AKI) caused by folic acid.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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