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Copper ionophore I

CAT: 0013-GTR19273328-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273328-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Copper ionophore I is an efficient carrier of copper ions that modulates intracellular copper levels to induce cuproptosis, with effects observed in cells such as 4T1 (IC50= 0.45 μM) and MDA-MB-231 (IC50= 1.21 μM) . It elevates ROS, leading to mitochondrial dysfunction, and decreases the expression of proteins FDX1, DLAT, and LIAS. Additionally, it can activate immune-related pathways, enhancing T cell infiltration, making it a valuable compound for cancer research.
CAS Number
101264-90-8
Smiles
O=C (NN=CC=1C=CC=CC1O) CCCCC
Molecular Formula
C13H18N2O2
Molecular Weight
234.3
Storage Conditions
-20°C
Notes
For research use only.

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