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LIFR/GPBAR1 modulator 1

CAT: 0013-GTR19273325-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273325-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LIFR/GPBAR1 modulator 1 is an orally active, potent GPBAR1 agonist (EC50= 0.2 μM) and LIFR inhibitor (IC50= 7.9 μM) . It enhances the expression of leukemia inhibitory factor (LIF) -mediated LIFR and GPBAR1 mRNA, while significantly reducing the expression of fibrosis markers (COL1A1, ASMA, and TGFβ), decreasing TIMP1 levels, and increasing MMP9 expression. LIFR/GPBAR1 modulator 1 is applicable for research into human fibrotic diseases.
Storage Conditions
-20°C
Notes
For research use only.

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