GPBAR1-IN-3

• UNSPSC Description:

  GPBAR1-IN-3 (Compound 14) is a selective GPBAR1 agonist (EC50=0.17 μM) and a CysLT1R antagonist[1].

• Target Antigen:

  G protein-coupled Bile Acid Receptor 1; Leukotriene Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Others

• Assay Protocol:

  https://www.medchemexpress.com/gpbar1-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(CC)COC1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1

• Molecular Weight:

  321.41

• References & Citations:

  [1]Fiorillo B, et al. Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1. J Med Chem. 2021 Nov 12.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2760546-05-0