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CYP1B1-IN-12

CAT: 0013-GTR19273137-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273137-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP1B1-IN-12 is a selective inhibitor of cytochrome P4501B1 (CYP1B1) with an IC50 value of 6.05 nM. It demonstrates exceptional selectivity, being over 1,600 times more selective for CYP1B1 compared to CYP1A1 and over 16,000 times compared to CYP1A2. CYP1B1-IN-12 enhances Paclitaxel-mediated apoptosis and restores sensitivity of A549/Tax cells to Paclitaxel. It also inhibits epithelial-mesenchymal transition, reducing cell migration and invasion. CYP1B1-IN-12 is applicable in cancer research, such as non-small cell lung cancer (NSCLC) .
Storage Conditions
-20°C
Notes
For research use only.

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