Products for Research Use Only

LMP-420

CAT: 0013-GTR19272977-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272977-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LMP-420 is a selective inhibitor of tumor necrosis factor-α (TNF-α) . It reduces the release of pro-inflammatory cytokines, such as IL-1β and IL-2, while inducing the expression of anti-inflammatory cytokine IL-10, and anti-apoptotic molecules SOCS-1 and Mn-SOD. LMP-420 also downregulates chemokines like IP-10 and MCP-1, which decreases immune cell infiltration. This compound shows potential for research into type 1 diabetes, inflammatory diseases such as colitis, and HIV-mycobacterium tuberculosis co-infection.
CAS Number
473870-63-2
Smiles
ClC1=NC (=NC2=C1N=CN2CCCCCB (O) O) N
Molecular Formula
C10H15BClN5O2
Molecular Weight
283.52
Storage Conditions
-20°C
Notes
For research use only.