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Salicylate choline

CAT: 0013-GTR19272953-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272953-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Salicylate choline is a derivative of Aspirin (acetylsalicylic acid) and is orally active. It significantly reduces the levels of IL-1β, IL-6, TNF-α, and IL-10 in cells. By inducing S phase cell cycle arrest and impairing DNA damage repair, salicylate choline enhances the antitumor activity of the CRM1 inhibitor Selinexor (KPT-330) . When combined with Selinexor, salicylate choline demonstrates excellent antitumor efficacy in mouse xenograft models with JeKo-1 cells. It is applicable in the research of rheumatism, inflammation, and cancer.
CAS Number
2016-36-6
Smiles
O=C ([O-]) C=1C=CC=CC1O.OCC[N+] (C) (C) C
Molecular Formula
C12H19NO4
Molecular Weight
241.29
Storage Conditions
-20°C
Notes
For research use only.

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