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CAXII-IN-3

CAT: 0013-GTR19272927-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272927-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAXII-IN-3 is a potent carbonic anhydrase (CA XII) inhibitor, with a Ki of 53 nM. It selectively inhibits various human CA isoforms, showing Ki values of 5.3 μM for CA I, 75 nM for CA II, 1.9 μM for CA IV, and > 10 μM for CA IX. Primarily targeting CA II and CA XII, CAXII-IN-3 reduces aqueous humor production. Additionally, it exhibits β3-AR agonist activity, leading to retinal blood vessel dilation and improved optic nerve perfusion. CAXII-IN-3 is applicable in the study of ocular diseases such as glaucoma.
Storage Conditions
-20°C
Notes
For research use only.

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P1704-50Active Recombinant Human CAXII Protein
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