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SC-919

CAT: 0013-GTR19272872-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272872-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SC-919 (LI-2124) is an orally active and selective inhibitor that targets inositol hexakisphosphate kinases (IP6K, including the subtypes IP6K1, IP6K2, and IP6K3), with an IC50 value of 0.65 nM for IP6K3. By inhibiting IP6K, SC-919 reduces the production of inositol pyrophosphates (such as InsP7), thereby inhibiting XPR1-mediated phosphate efflux from cells and increasing intracellular ATP levels. SC-919 shows potential for research in hyperphosphatemia associated with chronic kidney disease (CKD) .
CAS Number
2245949-62-4
Smiles
O=C1[C@]2 (C=3C (N1) =CC=C (C (O) =O) C3) CC[C@H] (OC4=C (Cl) C=C (Cl) C=N4) CC2
Molecular Formula
C19H16Cl2N2O4
Molecular Weight
407.25
Storage Conditions
-20°C
Notes
For research use only.

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