Products for Research Use Only

P2Y1 antagonist 4

CAT: 0013-GTR19272863-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272863-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P2Y1 antagonist 4 is a selective blocker of the P2Y1 receptor with excellent penetration across the blood-brain barrier. It inhibits ADP-induced increases in cytosolic Ca2+ mediated by the P2Y1 receptor in washed rabbit platelets (IC50 = 1.95 μM) and platelet aggregation (IC50 = 3.24 μM) . P2Y1 antagonist 4 significantly elevates nuclear Nrf2 protein levels in H2O2-treated HT22 cells. It reduces infarct size in a mouse acute myocardial infarction model and is applicable in research on ischemic stroke and myocardial infarction.
Storage Conditions
-20°C
Notes
For research use only.

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