P38-α MAPK-IN-11

CAT: 0013-GTR19274687-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274687-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

P38-α MAPK-IN-11 (Compound 4C) is a selective blood-brain barrier-penetrable inhibitor of P38α MAPK, with an IC50 of 43 nM. It exhibits minimal inhibitory activity against other MAPK isoforms, such as p38β, p38γ, and p38δ, with IC50 values of > 100 nM, > 100 nM, and 48.6 mM, respectively. In rat models resembling Alzheimer’s disease, p38-α MAPK-IN-11 demonstrates significant neuroprotective and anti-neuroinflammatory effects. This compound is valuable for Alzheimer's disease research.

Storage Conditions

-20°C

Notes

For research use only.

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P38-α MAPK-IN-11

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