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PZ-1129

CAT: 0013-GTR19274552-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274552-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PZ-1129 is a selective ligand for the 5-HT7 receptor (5-HT7 receptor) with a Ki value of 7 nM. It exhibits Ki values of 159 nM for the 5-HT1A receptor and 24 nM for the D2 receptor. PZ-1129 inhibits constitutive cyclic adenosine monophosphate (cAMP) production mediated by the Gs signaling pathway, with an EC50 of 13.7 nM. This compound is applicable for research into affective disorders such as depression and bipolar disorder.
CAS Number
1919029-61-0
Smiles
O=S (=O) (NC1CCN (CCOC=2C=CC=CC2C=3C=CC=CC3) CC1) C4=CC=C (F) C=C4
Molecular Formula
C25H27FN2O3S
Molecular Weight
454.56
Storage Conditions
-20°C
Notes
For research use only.

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