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BrP-LPA sodium

CAT: 0013-GTR19274440-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274440-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BrP-LPA sodium is a broad-spectrum antagonist of lysophosphatidic acid (LPA), demonstrating antagonistic activity towards LPA1 (IC50 = 4520 nM), LPA2 (IC50 = 468 nM), LPA3, and LPA4. Additionally, BrP-LPA sodium exhibits partial agonistic activity at LPA5 with an EC50 of 1282 nM. It also acts as an ATX inhibitor and effectively inhibits the migration and invasion of breast cancer cells. In mouse xenograft models of breast cancer, BrP-LPA sodium induces tumor regression and anti-angiogenic effects. This compound is applicable for breast cancer research.
CAS Number
944265-88-7
Smiles
O (C[C@H] (CC (P (=O) (O) O) Br) O) C (CCCCCCCCCCCCCCC) =O.[Na]
Molecular Formula
C20H41BrNaO6P
Molecular Weight
511.41
Storage Conditions
-20°C
Notes
For research use only.

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