BRP-821

• Description :

  BRP-821 is a soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 0.4 nM. BRP-821 can be used for the researches of inflammation, cardiovascular, metabolic and neurological disease [1].

• Product Name Alternative :

  FP30

• UNSPSC :

  12352005

• Target :

  Epoxide Hydrolase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

• Smiles :

  COC1=CC(C(F)(F)F)=C(C=C1)CNC(C2=CC=C3C(N=C(N3C)CC4=CC=C(C=C4)C5(CC5)C(F)F)=C2)=O

• Molecular Formula :

  C29H26F5N3O2

• Molecular Weight :

  543.53

• References & Citations :

  [1]Çalışkan K, et al. Harnessing structure-activity relationships to repurpose the FLAP inhibitor BRP-7 into potent and selective sEH inhibitors. Bioorg Chem. 2025 Oct;165:108997.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported