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P2L-003

CAT: 0013-GTR19274229-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274229-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P2L-003 is a selective PAR2 antagonist with an IC50 of 0.62 μM in HT-29 cells. It blocks PAR2-mediated Ca2+ mobilization without affecting signaling through PAR1, PAR4, or ATP. P2L-003 dose-dependently inhibits downstream MAPK signaling cascades, including the phosphorylation of ERK1/2 and p38, and is applicable in colon cancer research.
CAS Number
1359416-20-8
Smiles
O=C (N (C=1C=CC=CC1) CC2=NN (C3=C2CN (CC3) S (=O) (=O) CC=4C=CC=CC4Cl) C) C
Molecular Formula
C23H25ClN4O3S
Molecular Weight
472.99
Storage Conditions
-20°C
Notes
For research use only.

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