Products for Research Use Only

(R) -KMH-233

CAT: 0013-GTR19267000-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19267000-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -KMH-233 is an isomer of KMH-233, which can serve as a reference compound in experiments. KMH-233 functions as a potent, reversible, and selective inhibitor of L-type amino acid transporter 1 (LAT1), effectively hindering the uptake of LAT1 substrate, l-leucine (IC50=18 μM), and also inhibiting cell growth. Even at a low concentration of 25 μM, KMH-233 significantly enhances the efficacy of Bestatin and cisplatin.
CAS Number
2994330-89-9
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C (=O) C1=CC (C[C@H] (C (O) =O) N) =CC=C1) C=2N3C (C (C#N) =C (C2C#N) C4=CC=C (OCC (NC) =O) C=C4) =NC=5C3=CC=CC5
Molecular Formula
C32H25N7O5
Molecular Weight
587.58
Storage Conditions
-20°C
Notes
For research use only.