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Cyclic GMP (TBAOH)

CAT: 0013-GTR19266480-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19266480-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclic GMP TBAOH is an endogenous second messenger that triggers the production of interferons in response to cytosolic DNA. It activates the stimulator of interferon genes (STING), initiating a signaling cascade that produces type I interferons and other immune mediators. The conjugate of Cyclic GMP TBAOH and AMP, known as Cyclic-GMP-AMP, can induce IRF3 phosphorylation and nuclear translocation to enhance antiviral immune responses. Additionally, Cyclic GMP TBAOH may activate PDE to degrade cAMP, inhibit the calcium current ICa in cardiomyocytes, and regulate myocardial contractility. Its derivative, 8-Br-cGMP, exhibits antiplatelet activity, making Cyclic GMP TBAOH useful for research in antiviral immunity and cardiovascular diseases.
Field of Research
Immunology & Inflammation, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.

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