SGK1-IN-1

CAT: 0931-T12890Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T12890Size:1 mg

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CAS Number

1279829-87-6

Target

SGK

Related Pathways

Metabolism

Bioactivity

SGK1-IN-1 (compound 14n) is a highly potent SGK1 (Serum/Glucocorticoid Regulated Kinase 1) inhibitor, with inhibitory activities of 41 nm, 128 nm, and 310 nm against hSGK1/2/3 at 500 μM ATP, respectively, and can be used for studying SGK1-related cancers and metabolic diseases.

Smiles

O=S(=O)(NC=1C=CC(=CC1)C2=NC=3NN=C(N)C3N=C2)C4=CC(Cl)=CC=C4F

Molecular Formula

C17H12ClFN6O2S

Molecular Weight

418.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Sgk1-IN-1

CAS Number	1279829-87-6
PubChem CID	71506845
IUPAC Name	N-[4-(3-amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-5-chloro-2-fluorobenzenesulfonamide
Molecular Formula	C17H12ClFN6O2S
Molecular Weight	418.8
XLogP	2.4
Topological Polar Surface Area	135
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Heavy Atom Count	28
Formal Charge	0
Complexity	644

SMILES

C1=CC(=CC=C1C2=NC3=NNC(=C3N=C2)N)NS(=O)(=O)C4=C(C=CC(=C4)Cl)F

InChI

InChI=1S/C17H12ClFN6O2S/c18-10-3-6-12(19)14(7-10)28(26,27)25-11-4-1-9(2-5-11)13-8-21-15-16(20)23-24-17(15)22-13/h1-8,25H,(H3,20,22,23,24)

InChIKey

DDKHTWASHUKHLD-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1279829-87-6

CID: 71506845

Formula: C17H12ClFN6O2S

MW: 418.8

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	418.8
XLogP3	2.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	418.0415007
Monoisotopic Mass	418.0415007
Topological Polar Surface Area	135 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	644
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
BA8344-5	SGK1-IN-1
A20929-50	SGK1-IN-1 50mg
A20929-2	SGK1-IN-1 2mg
A20929-10	SGK1-IN-1 10mg
A20929-100	SGK1-IN-1 100mg
A20929-25	SGK1-IN-1 25mg
A20929-5	SGK1-IN-1 5mg
334086-01	SGK1
P32776	PExpress-1-Sgk1 (rat)
PVT41890	pExpress-1-Sgk1 Plasmid

SGK1-IN-1

Chemical Information

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