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MO-2097

CAT: 0013-GTR19266243-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19266243-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MO-2097 is an inhibitor of RAF-1 and HIF-1α. It destabilizes RAF-1, reducing EMT-related transcription factors and mesenchymal markers. MO-2097 suppresses HIF-1α protein expression under hypoxic or hypoxia-mimicking conditions via hnRNPA2B1. It induces mitochondrial ROS production, leading to cell apoptosis. By inhibiting the RAF/MEK/ERK signaling pathway, MO-2097 effectively prevents colorectal cancer metastasis. It also inhibits tumor growth in human colorectal cancer HCT116 cell xenograft mouse models. MO-2097 is applicable for colorectal cancer research.
CAS Number
2744300-63-6
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction
Smiles
OC=1C=C (O) C=C (C1) C=2OC=3C=C4OCC (=CCC4=CC3C2) C
Molecular Formula
C19H16O4
Molecular Weight
308.33
Storage Conditions
-20°C
Notes
For research use only.

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