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BAY-091

CAT: 0804-HY-139868-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139868-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-091, a chemical probe, is a potent and highly selective inhibitor of the kinase PIP4K2A.
CAS Number
2922280-34-8
UNSPSC
12352005
Target
PI5P4K
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bay-091.html
Purity
98.45
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC[C@@H](NC1=C(C#N)C(C2=CC=C(C3=CC=CC(C)=C3F)C=C2)=NC4=CN=CC=C14)C(O)=O
Molecular Formula
C26H21FN4O2
Molecular Weight
440.47
References & Citations
[1]Wortmann L, et al. Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A. J Med Chem. 2021 Nov 11;64 (21) :15883-15911.|[2]Souza G F, et al. TARGETING GAMMA GLOBIN SYNTHESIS: THE ACUTE EFFECTS OF PIPKIIA INHIBITION AND PTDIN5P STIMULATION IN MYELOID CELL LINES K562 AND KU812[J]. Hematology, Transfusion and Cell Therapy, 2024, 46: S62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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