Products for Research Use Only

DAurAB5

CAT: 0013-GTR19264639-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264639-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DAurAB5 is a dual PROTAC degrader targeting Aurora-A (DC50= 8.8 nM) and Aurora-B (DC50= 6.1 nM) . It induces the degradation of Aurora-A and Aurora-B, leading to reduced N-Myc levels and decreased viability of IMR32 neuroblastoma cells. Additionally, dAurAB5 downregulates the levels of AAK1, PTK2, GAK, and TTK. This compound is applicable in cancer research, including neuroblastoma.
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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