Products for Research Use Only

LO-3-63

CAT: 0013-GTR19263878-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263878-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Storage Conditions
-20°C
Notes
For research use only.