Products for Research Use Only

EGFR-IN-165

CAT: 0013-GTR19263860-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263860-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-165 is a potent EGFR inhibitor with IC50 values of 17.18 nM for EGFRL858R/T790M kinase and 64.74 nM for EGFRWT. Its IC50 values for NCI-H1975 and A431 cell lines are 2.17 μM and 6.2 μM, respectively. EGFR-IN-165 significantly inhibits cell migration, induces G1 phase cell cycle arrest, and causes apoptosis. It is suitable for research on cancers such as non-small cell lung cancer, colorectal cancer, and head and neck squamous cell carcinoma.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.